Table 3: Lipid and mitochondrial abnormalities causing NS.

Gene Protein Inheritance Onset Comments
ApoE Apolipoprotein E AD Adulthood Lipid glomerulopathy with lipid thrombi, Asian descent
LCAT Lecithin:cholesterol acyltransferase AR Adulthood Corneal opacities, hepatosplenomegaly, anemia, CKD
CoQ6 Coenzyme Q6 AR Infancy NS, sensorineural deafness, ESRD