Fig. (1) Noncytolytic CD8⁺ T Cell Mediated Suppression of HIV NL4-3 Pseudotyped Virus Replication. CD4⁺ T lymphocytes were infected with NL4-3 pseudotyped virus and exposed to CD8⁺ T lymphocytes. (N=4) % Control Infection is the amount of infection relative to the control NL4-3 infected CD4⁺ T-lymphoctyes. The cutoff for the upper limit for suppression was 10% infection, a 1-log reduction, in the CD4⁺ co-cultures with JR HVS CD8⁺ and HS HVS CD8⁺. ^* p = 0.023 for both JR and HS HVS CD8⁺ compared to nEW CD8⁺, Student t-Test.