Fig. (4) Transcriptional Elongation/Splicing during Noncytolytic CD8 T cell mediated Suppression of HIV Replication. Using the derived equation [NSL/[SL x [NSS/SS]]], this figure illustrates the calculated elongation/splicing effects from non-cytolytic CD8+ suppression as determined by the “fold difference between suppressed and non-suppressed” viral cultures. By accounting for inhibition at transcriptional initiation, ratio values of JR = 0.6, HS = 0.6, EW = 0.8 indicate the likely absence of suppression at elongation and/or splicing (N = 16, N = 12, and N = 16, respectively).