APPENDIX B The removal of both ends of C5A abrogates its capacity to inhibit vaginal and rectal HIV transmission in humanized mice.Same as Appendix.(A) except that indicated on the right are the amino acid sequences of the C5A peptides (100 µM) applied vaginally (A) or rectally (B) 15 min prior to a vaginal (A) and rectal (B) HIV (JR-CSF) challenge.