Protection Efficacy of C5A Against Vaginal and Rectal HIV Challenges in Humanized Mice

Fig. (3) Median-effect plots describing the impact of (A) vaginal (regression coefficient, r = 0.956) and (B) rectal (regression coefficient, r = 0.955) C5A dosing on HIV preventions in humanized BLT mice. The model allows a range (50-97%) of C5A effective concentrations to be calculated for both compartments (C).