Table 3: Fixed effect analysis of overall, general and high risk groups.

Group Effect Size and 95% CI Test of Null (2-Tail) Heterogeneity
No. of Studies Point Estimate Lower Limit Upper Limit Z-value P-value Q-value df (Q) P-value I-Squared
Fixed Effect Analysis
1 15 2.80 2.68 2.93 -151.01 0.00 1147.11 14 0.00 98.78
2 5 5.25 4.99 5.51 -109.79 0.00 162.83 4 0.00 97.54
Overall 20 3.71 3.59 3.83 -185.79 0.00 1650.65 19 0.00 98.85
Mixed effects analysis of general, high-risk and overall populations
1 15 2.71 1.74 4.21 -15.48 0.00
2 5 5.64 2.99 10.35 -8.37 0.00
Overall 20 3.44 2.39 4.91 -17.50 0.00