HIV–1 Antigens in Neurons of Cocaine-Abusing Patients

Table. 1: HIV-1 Positive^a and Control^b Patients – Diagnostic^a and Virological^b Data

Subject	Age/Sex	Cocaine Abuse	Other Risk Factors	Neuropathological Diagnosis	Neuronal Staining^c
Subject	Age/Sex	Cocaine Abuse	Other Risk Factors	Neuropathological Diagnosis	gp120	p24	Nef
HIV 1	46 M	No	Morphine^d	White matter pallor, gliosis	+	+	N.D.
HIV 2	29 F	Yes	No	Alzheimer type II gliosis	+	+	+
HIV 3	58 F	Yes	No	N.D.	+	N.D	N.D.
HIV 4	44 M	Yes	Alcoholism	Alzheimer type II gliosis; HIV encephalitis	+	N.D.	N.D.
HIV 5	34 F	Yes	No	HIV encephalitis; cryptococcal meningitis	+	+	+
HIV 6	42 M	No	No	Minimal non-diagnostic abnormalities	–	–	–
Ctrl 1	69 M	No	No	ALS; Anoxic-ischemic encephalopathy; laminar necrosis in occipital cortex	–	–	–
Ctrl 2	66 M	No	No	ALS	–	N.D.	N.D.
Ctrl 3	86 F	No	No	No neuropathology	–	N.D.	N.D.
Ctrl 4	90 F	No	No	No neuropathology	–	N.D.	N.D.

^a All HIV subjects except #6 had neurocognitive diagnosis of HAD.

^b All controls were HIV-1 negative. Control 1 and 2 had amyotrophic lateral sclerosis (ALS).

^c Post-mortem frontal lobe and hippocampus.

^d Morphine for pain control.