Fig. (3) Quantum computation steps with miRNAs. Basically, two resources, computation steps (time) and memory (space), limit the ability of digital computers to solve large problems. Computer devices consist of three core components, namely, memory, a resister, and a Turing machine, which was first described by A. Turing in 1936 [38]. Older computer systems can search objects one at a time; however, the quantum computer by Shor [31] can perform polynomial computation with a random number generator. The system of miRNAs may be closely analogous to that of a quantum computer. Seven sequences in the seed of miRNA may simultaneously target multiple miRNAs with incomplete pairing, and therefore, the seed sequences of the genomic miRNA, which are integrated into the host genome corresponding to the new algorithm shown in Fig. 2, may correspond to quantum memory (space). The resident miRNA sequences may be analogous to a resistor. A Turing machine can read and decipher the genomic miRNA code, and then the information from the genomic miRNAs could be stored as a resistor in resident miRNA sequences. The stored information could be uploaded and/or downloaded into the quantum memory from the resistor. Therefore, the miRISC, which reads seed sequences, may correspond to a Turing machine. In the case of quantum computing (time) based on the seed sequences of miRNA, if the seed sequences are composed of the quantum bits | 0 > and | 1 > ( | u >, | g >, | c > or | ug >, | uc >, | cg > etc as shown in the panel), seven qubits of memory superpose approximately 27 states. With only 500 human miRNAs as 500 records of quantum memory, about 64,000 targets could be selected at one time. Since there are fewer than 20,000 human protein coding genes, the genes can effectively be simultaneously controlled by miRNAs. The complete decipherment of the miRNA code has only now begun.
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