Fig. (5) Comparison of Ad12 Spm2 E1A-mediated dose-dependent activation of transcription in MV3 cells between the del 59 SP1, the del -59, the del -67, the del -262 and the complete 804 bp HHV-8 promoter constructs. The transfection procedure was as described in Fig. (4). Mean relative promoter activities compared to controls and standard deviations obtained from nine transfections in triplicate are shown. The transfection efficiency was 50 ± 10%.