| Human | miRNA Involvement | |||||
|---|---|---|---|---|---|---|
| Cancer | Oncomir | Suppressor miRNA | Oncogene Target | References | ||
| Oncoviral integration-induced | ||||||
| Lymphomaa) | mir-1204 | [166] | ||||
| (PVT-1) | ||||||
| Erythroleukemiaa) | miR-17-92 | [165] | ||||
| (Fli-3) | ||||||
| T-cell leukemia | miR-106a | c-myc | [164] | |||
| (Kis2) | ||||||
| miR-19b-2 | ||||||
| miR-92-2 | ||||||
| miR-20b | ||||||
| B-cell leukemia | miR-155 | miR-17-92 | [44] | |||
| (BIC) | [142] | |||||
| Non-oncoviral | ||||||
| Brain cancer | miR-21 | miR-181 | [169] | |||
| miR-221 | [135] | |||||
| Breast cancer | miR-125b | [134] | ||||
| miR-145 | ||||||
| miR-21 | ||||||
| miR-155 | ||||||
| Chronic | miR-15 | BCL2 | [120, 170] | |||
| lymphocytic | miR-16 | [119] | ||||
| leukemia | ||||||
| Gastric cancer | miR-34b | miR-128b | [171] | |||
| miR-34c | miR-129 | |||||
| miR-128c | miR-148 | |||||
| miR-106b | [172] | |||||
| miR-222 | ||||||
| Colorectal | miR-143 | v-Ki-ras (KRAS) | [43] | |||
| neoplasia | miR-145 | [173] | ||||
| Pancreatic cancer | miR-21 | miR-375 | [174] | |||
| miR-221 | ||||||
| miR-222 | ||||||
| miR-181a, b, d | ||||||
| miR-155 | [145] | |||||
| Hepatocellular | miR-18 | miR-199 | [175] | |||
| carcinoma | miR-224 | miR-195 | ||||
| miR-200 | ||||||
| miR-125 | ||||||
| miR-101 | v-fos | [176] | ||||
| Lung cancer | miR-17-92 | let-7 | Ras | [136] | ||
| let-7a | [137] | |||||
| [177] | ||||||
| [138] | ||||||
| Papillary | miR-222 | [130] | ||||
| thyroid | miR-146 | [178] | ||||
| carcinoma | miR-181 | |||||
| Teasticular | miR-372 | [179] | ||||
| germ cell | miR-373 | |||||
| tumor | ||||||
| Ovarian cancer | miR-21 | [116] | ||||
| miR-141 | ||||||
| miR-200a, b, c | ||||||
| miR-203 | ||||||
| miR-205 | ||||||
| (In sera specimens) | ||||||