| Gene | Function |
|---|---|
| E1 | Initiation of DNA replication |
| E2 | Transcriptional regulation/DNA replication |
| E3 | ? |
| E4 | Cytoskeleton disruption? |
| E5 | Transforming protein, interacts with growth factor receptors |
| E6 | Transforming protein, binds to p53, leading to degradation |
| E7 | Transforming protein, binds to pRB |
| E8 | ? |
| L1 | Major capsid protein |
| L2 | Minor capsid protein |