| Vendor | System | Marker | Method/Generation/Format | Characteristics |
|---|---|---|---|---|
| ABBOTT | ARCHITECT | Antibodies + Antigen | Chemiluminescence (CMIA)/4th generation/Sandwich | Modular system; 200-800 determinations/hour |
| Primary tube and aliquot / barcode | ||||
| 25 refrigerated reagents per module / stable 30 days / 5 hours of autonomy | ||||
| 135 samples / module / continuous loading / immediate emergency processing (35 positions/module) | ||||
| Response time 29 minutes | ||||
| Sample volume 150 ul / automatic repetitions / conditional tests | ||||
| Pressure differential clot detection | ||||
| Intelligent wash system. Minimal carry-over (1 ppm) | ||||
| Reagents with barcode: Information on batch, expiry date, calibration curves | ||||
| Long calibration curve stability | ||||
| Automatic internal quality control system (Levey-Jennings) | ||||
| Remote diagnostics (AbbottLinkTM). | ||||
| Connection to Laboratory Information System (LIS) | ||||
| ROCHE | COBAS | Antibodies + Antigen | Chemiluminescence (ECLIA)/4th generation/Sandwich | Modular system; 88-170 determinations/hour |
| Primary tube and aliquot / barcode | ||||
| 18-25 refrigerated reagents per module | ||||
| 100-150 samples / module / continuous loading / immediate emergency processing | ||||
| Response time 18 minutes | ||||
| Sample volume <50 ul /automatic repetitions. Conditional tests | ||||
| Disposable tips and cups that prevent contamination | ||||
| Reagents with barcode: Information on batch, expiry date, calibration curves | ||||
| Calibration stable 28 days. | ||||
| Connection to Laboratory Information System (LIS) | ||||
| IZASA | ACCESS 2 UnicelTM DxI 400-800 | Antibodies + Antigen | Chemiluminescence/4th generation/Sandwich | Modular system; 200-400 determinations/hour |
| Primary tube / automatic taking of aliquots and release of primary tube in 5 minutes / barcode | ||||
| 50 refrigerated reagents per module / stable 30 days / autonomy 1200 tests | ||||
| 120 samples / module / continuous loading / immediate emergency processing | ||||
| Response time 55; | ||||
| Sample volume <50 ul / automatic repetitions / conditional tests | ||||
| Fixed tip, no carry-over, wash system with carry-over <10 ppm | ||||
| Reagents with barcode: Information on batch, expiry date, calibration curves | ||||
| Calibration curve stability 26 days | ||||
| Connection to Laboratory Information System (LIS) | ||||
| DIASORIN | LIAISON XL | Antibodies + Antigen Separate | Chemiluminescence (CLIA)/4th generation/Sandwich | 171 determinations/hour |
| Primary tube / barcode | ||||
| 250 refrigerated reagents per module / stable 8 weeks | ||||
| 120 samples / continuous loading / immediate emergency processing | ||||
| Response time 40 minutes | ||||
| Sample volume 350 ul / automatic repetitions / conditional tests | ||||
| Reagents with barcode: Information on batch, expiry date, calibration curves | ||||
| Calibration curve stability 15-30 days | ||||
| Connection to Laboratory Information System (LIS) | ||||
| Disposable tip / no carry-over / clot detection | ||||
| Independent antigen and antibody signals / sensitivity of p24 Ag: 1.26 IU/ml | ||||
| SIEMENS | CENTAUROXP and CP | |||
| Antibodies | Chemiluminescence/3rd generation/Sandwich | Disposable tips. Capacity for 840 tips simultaneously | ||
| Incubation time 58 min | ||||
| Sample volume 50 ul | ||||
| Calibration every 21 days, on-board stability 42 days | ||||
| Antibodies +Antigen | Chemiluminescence/4th generation/Sandwich | Disposable tips. Capacity for 840 tips simultaneously | ||
| Response time 58 min | ||||
| Sample volume 100 ul | ||||
| Calibration every 21 days, on-board stability 42 days | ||||
| Sensitivity p24 Ag 1.15 IU/ml | ||||