| Strickler, et al. J Natl Cancer Inst 2005; 97 [8] | Theiler, et al. Obstet Gynecol 2010; 115 [6] | ||||
|---|---|---|---|---|---|
| HIV-Positive | HIV-Negative | HIV-Positive | HIV-Negative | ||
| n=1848 | n=514 | n=634 | n=264 | ||
| Age | <26 | 8% | 17% | 58.0% | 58.7% |
| 26-29 | 10% | 12% | |||
| 30-35 | 28% | 24% | |||
| 36-45 | 44% | 39% | 37.5% | 36.4% | |
| >45 | 10% | 7% | 4.4% | 4.9% | |
| Lifetime sex partners | 0-4 | 22% | 20% | not reported | |
| 5-9 | 18% | 22% | |||
| 10-49 | 32% | 37% | |||
| 50+ | 27% | 21% | |||
| HPV seropositive* | not reported | 98.3% | 93.2% | ||
| New HPV detection in absence of sexual activity | HPV16: 3.3/P-Y | ||||
| CD4>500: 13% | HPV18: 3.8/P-Y | ||||
| CD4 200-500: 18% | 5% | HPV31: 1.1/P-Y | |||
| CD4<200: 22% | HPV35: 0.6/P-Y | ||||
| HPV45: 3.7/P-Y | |||||
| Evidence for association with immune suppression | Increasing incidence with decreasing CD4+ T-cell count | HIV-infected women 1.8-8.2 times more likely to have recurrent shedding than HIV-uninfected | |||