Fig. (4) Graphical representation of the genes that were
differentially expressed in at least two studies reporting the
differential expression between HPV-positive versus HPV-negative
head-and-neck cancers. The signatures represent the differentially
expressed genes as follows: Schlecht_HNSC [49] and
Slebos_HNSC [47], HPV-positive versus HPV-negative head-and-neck
squamous cell carcinoma; Martinez_oropharyngeal [48],
HPV-positive versus HPV-negative oropharyngeal squamous cell
carcinoma; Pyeon_HPV_positive_cancers [50], HPV-positive head-and-
neck cancer (HNC) and cervical cancer versus HPV-negative
HNC. The upregulated genes are depicted in orange, downregulated
in green, and not differentially expressed in white. The annotations
of the genes are included as Supplementary Table 1.