Table 1.: HBV Genotypes and the Comparison of Virological and Clinical Differences [9]

Clinical and Virological Characteristics Genotypes
A B C D
Mode of transmission Horizontal Vertical/Perinatal Vertical/Perinatal Horizontal
Tendency to chronic state Higher Lower Higher Lower
HBeAg seroconversion Earlier Earlier Later Later
LC and HCC outcomes Better Better Worse Worse
Frequency of PC (G1896A) mutation Lower Higher Lower Higher
Frequency of BCP (T1762/A1764) mutation Higher Lower Higher Lower

HBeAg= Hepatitis B e Antigen; LC= Liver Cirrhosis; HCC= Hepatocellular Carcinoma; PC= Precore; BCP= Basal Core Promoter.