Epstein- Barr Virus: Clinical and Epidemiological Revisits and Genetic Basis of Oncogenesis

Table 1: Expression of EBV-latency associated genes during latency programs [⁸⁷].

Latency program	EBV gene expressed						occurrence
Latency program	EBERs	EBNA1	LMP1	LMP2A	EBNA2	EBNA3	occurrence
0	+	ND	-	+	-	-	Memory B cells in peripheral blood
I	+	+	-	-	-	-	BL, PEL
II	+	+	+	+	-	-	HD
III	+	+	+	+	+	+	PTLD
IV	ND	ND	-	ND	+	ND	Infectious mononucleosis, PTLD

BL, Burkitt lymphoma; HD, Hodgkin lymphoma; ND, Not determined; PEL, primary effusion lymphoma; PTLD, post-transplant lymphoproliferative disease; +, expressed; -, not expressed.