The Open Medicinal Chemistry Journal

ISSN: 1874-1045 ― Volume 12, 2018


Ernest A. Adeghate
Department of Anatomy
College of Medicine & Health Sciences
UAE University
Al Ain
United Arab Emirates

Editorial Board Members:

R. Amoroso (Biography
R. Amoroso

Prof. Rosa Amoroso completed the degree in Pharmaceutical Chemistry and Technology and the PhD in Organic Chemistry at University of Bologna. Nowadays she is Associate Professor of Medicinal Chemistry at University of Chieti, Italy. The scientific interests of Prof. Rosa Amoroso are mainly directed towards medicinal chemistry and the research topics are compunds active on Peroxisome proliferator-activated receptors (PPAR) and Nitric Oxide Synthase (NOS).


Department of Pharmacy
University of Chieti

G. Bertho (Biography
G. Bertho

Dr. Bertho, Ph.D, is engineer of the French National Center of Research. He works in an interdisciplinary environment at Paris Descartes University, one of the main parisian medical university. Dr. Bertho was pioneering in France since 1993 in the field of ligand-based interaction studies by NMR in collaboration with several private companies and developed an automatic analysis of docking data (

Dr. Bertho manages the human health project 'MetaboParis-Sante' identified in the French metabolomic network (RFMF). He is working to promote NMR in a clinical setting for the first time in France and to create the national center of reference in metabolomics by NMR.


Laboratoire de Chimie et Biochimie Pharmacologiques et Toxicologiques
Universite Paris Descartes

C. Bretti (Biography
C. Bretti

Dr. Clemente Bretti graduated in Chemistry with first class honours in July 2003 at University of Messina, Italy. He attended research doctorate in Chemical Sciences “Analytical chemistry” in the three-year course (2004-2007) at the University of Messina. Since Dec 30, 2008, he is a fixed-term Technician in the Department of “Scienze Chimiche” at the University of Messina. His research is mainly focused on the study of thermodynamics of solutions with particular reference to: (a) Study of the acid-base behavior and of the sequestering ability of different ligands of biological and environmental interest, and (b) Solubility and dependence on ionic strength. Dr. Bretti is a co-author of 46 scientific publications in various international journals.


Department of “Scienze Chimiche”
University of Messina

S.M. Cascioferro (Biography
S.M. Cascioferro

Dr. Stella Cascioferro graduated with an honors degree in pharmacy in 1999; she became a Ph.D. in Medicinal Chemistry from the University of Palermo in 2004. The same year, she joined the Physical and Theoretical Chemistry Laboratory, University of Oxford. Her research interests include the design, synthesis, and biological evaluation of heterocyclic compounds as antitumoral and antinfective agents. Currently she is working in the Department STEBICEF (University of Palermo, Italy). Dr. Stella Cascioferro is the author of 40 scientific papers published in the peer reviewed international journals and she also reviewed several journals in the field of medicinal chemistry.


Department of Biological Sciences and Technologies Chemistry and Pharmaceuticals Section of Pharmaceutical Chemistry and Technologies
University of Palermo

D. Laurent (Biography
D. Laurent

Dr. Laurent Désaubry was promoted CNRS research director (corresponds to full professor) in 2014, and also became professor at Tianjin University of Science and Technology (TUST), China, in 2015. He has published 70 articles and 7 patents. His current main research interests concern the development of prohibitin ligands, non-peptide prokineticin receptor 1 agonists and new synthetic methodologies in organic synthesis (website:


Laboratory of Innovation Therapeutics Pharmacological faculty
CNRS University of Strasbourg

A.S. Mayhoub (Biography
A.S. Mayhoub

Dr. Mayhoub (PharmD) had a PhD degree (2012) in Medicinal Chemistry from Purdue University, USA. He was a postdoctoral fellow at University of Michigan (2013) and currently he is a faculty at Al-Azhar University and Zewail City for Science and Technology (Egypt). His main contributions in the field of Medicinal Chemistry included development of several cancer chemopreventives, aromatase inhibitors, and antiflaviviral agents (Dengue virus, West-Nile virus and HCV). He discovered phenylthiazoles as a new antibacterial class of compounds for treatment of notorious bacterial strains MRSA and VRSA.


Department of Organic Chemistry
College of Pharmacy
Al-Azhar University

K. Prokai-Tatrai (Biography
K. Prokai-Tatrai

Dr. Prokai-Tatrai is a Professor of Pharmaceutical Sciences at UNT System College of Pharmacy at Fort Worth where she is an award winning researcher and pharmacy educator. Her primary research interest has been on innovative and multidisciplinary projects focusing on medicinal chemistry-driven drug design and delivery into the central nervous system. A best testimony of a very recent success of her lab has been published in Science Translational Medicine describing the very first brain-selective delivery of estrogens based on a unique bioprecursor prodrug approach. She has six issued US patents and has been an editorial board member of numerous journals and an academic editor of a successful special issue on neuroprotection.


Department of Pharmaceutical Sciences
University of North Texas Health Science Center
Fort Worth, TX

S.K. Saraf (Biography
S.K. Saraf

Dr. Shailendra K. Saraf has done B. Pharm., M. Pharm., Ph.D., LL.B. He is a Professor of Pharmaceutical Chemistry and presently working as Director (Pharmacy), B.B.D.N.I.I.T., Lucknow, India. He has more than twenty six years of industrial, teaching and research experience. His major research interests include Synthetic Medicinal Chemistry, Phytopharmaceutical Chemistry and Nanochemistry. He has published more than 150 papers in national and international journals and conferences, and seventeen books/book chapters. He has delivered more than three dozen invited/plenary lectures and is a recipient of eight prestigious awards.


Faculty of Pharmacy
Babu Banarasi Das Northern India Institute of Technology (BBDNIIT)

D. Sun (Biography
D. Sun

Dr. Dianqing Sun is an Associate Professor of Pharmaceutical Sciences at the Daniel K. Inouye College of Pharmacy, University of Hawaii at Hilo. Before joining UH-Hilo, he was a Research Associate in the Department of Pharmaceutical Sciences of the College of Pharmacy, University of Tennessee Health Science Center. Dr. Sun received his Ph.D. from the University of Memphis, Organic Chemistry, and received his postdoctoral training in Medicinal Chemistry at the University of Tennessee. His Research is focused on the discovery and development of novel small molecule and natural product-inspired antibacterial, anticancer, and cancer chemopreventive agents, using classical organic synthesis and high-throughput chemistry approach, followed by traditional medicinal chemistry optimization of emerging lead compounds.


Department of Pharmaceutical Sciences
The Daniel K. Inouye College of Pharmacy
University of Hawai'i at Hilo
Hilo, HI

A. Vassallo (Biography
A. Vassallo

Antonio Vassallo obtained his master degree with laude on Pharmacy in 2002. November 2005 he obtained his Specialization in Hospital Pharmacy with laude. 2010 he obtained his Ph.D. discussing a doctoral thesis “Identification of new potential inhibitors of Hsp90, a promising target in cancer therapy”. He spent in 2006 and 2009 a traineeship of seven months at the Molecular Oncology Laboratory of Sigma-Tau (Rome). Since 2010, Assistant Professor at the University of Basilicata. Research objectives: The main field of research deals with studies of biologically active compounds isolated from food and medicinal plants and their drug delivery systems.


Department of Science
University of Basilicata

G. Ascoli
Molecular Neuroscience Department, George Mason University
Krasnow Institute for Advanced Study
Fairfax, VA

J.B. Chaires
Department of Medicine, Health Sciences Center
University of Louisville
James Graham Brown Cancer Center
Louisville, KY

J.-W. Chern
School of Pharmacy
College of Medicine
National Taiwan University

R. Eritja
Department of Structural Biology
Instituto de Biología Molecular de Centro de Investigación y Desarrollo

V.J. Hruby
Department of Chemistry
University of Arizona
Tucson, AZ

M. Kassiou
Faculty of Health Sciences
University of Sydney

T. Kietzmann
Faculty of Chemistry/Biochemistry
University of Kaiserslautern

R. McGeary
Chemistry Department (School of Molecular and Microbial Sciences)
The University of Queensland

Y. Okada
Faculty of Pharmaceutical Sciences
Kobe Gakuin University

G. Perry
Department of Biology
The University of Texas at San Antonio
College of Sciences
San Antonio, TX

M. Poirot
Sterol Metabolism and Therapeutic Innovations in Oncology
Cancer Research Center of Toulouse
University Toulouse

J. Sebastian
Department of Infectious Diseases
Center for Molecular Biology
Laboratory Corporation of America
Research Triangle Park, NC

T.W. Stone
Institute of Biomedical & Life Sciences
University of Glasgow

K. Tekes
Department of Pharmacodynamics
Semmelweis University

L.I. Wiebe
Division of Oncological Imaging, PET Centre
Cross Cancer Institute
Edmonton, AB

Y.H. Wong
Division of Life Science and the Biotechnology Research Institute
The Hong Kong University of Science and Technology
Hong Kong

A. Ammazzalorso (Biography
A. Ammazzalorso

Dr. Alessandra Ammazzalorso obtained her PhD in Pharmaceutical Sciences from the University of Chieti (Italy) in 2001. Since 2004 she is Assistant Professor at Pharmacy Department of University of Chieti. Her research interests include the design, synthesis and biological evaluation of novel small molecules, mainly compounds targeting Peroxisome Proliferator-Activated Receptors, aromatase and nitric oxide synthase.


Department of Pharmacy
University “G.d’Annunzio”

J.B. Bremner (Biography
J.B. Bremner

Emeritus Professor John Bremner holds a PhD in organic chemistry from the Australian National University, Canberra. He was formerly Professor of Organic Chemistry in the School of Chemistry, University of Wollongong, Wollongong, Australia. His research interests cover heterocyclic and medicinal chemistry, including the design and development of new anti-bacterial agents. He has over 220 scientific publications, and is on the Editorial Board of a number of journals.


Department of Chemistry
University of Wollongong

F.P. Busardò (Biography
F.P. Busardò

Dr. Francesco Paolo Busardò obtained his Bachelor’s Degree with Honors in Medicine and Surgery at the University of Palermo (Italy); winning the Prize for the Best Thesis. He did his MSc in Forensic Toxicology from the University of Glasgow (Scotland) and a PhD in Forensic Science from “Sapienza” University of Rome (Italy). He currently works as forensic toxicologist in “Sapienza” University of Rome. He focused most of his research on γ-Hydroxybutyric acid (GHB) pharmacology, toxicology and analytical aspects, publishing more than 20 papers in this field. He is author of about 90 papers with I.F., with a total I.F. higher than 250 and h-index of 10.


Dep. of Anatomical, Histological, Forensic and Orthopaedic Sciences , Unit of Forensic Toxicology (UoFT), Sapienza
University of Rome

H. Kalasz (Biography
H. Kalasz

Dr. Kalász is employed bythe Department of Pharmacology and Pharmacotherapy, Semmelweis University, Budapest, Hungary. He hasexperience in the isolation of natural products, pharmacokinetics and metabolism. He worked at Yale University (New Haven, CT, USA and was a Visiting Professor in the Department of Pharmacology and Cell Biophysics, University of Cincinnati, Cincinnati, OH, USA. Dr. Kalász holds various ranks of editorial boards at Journal of Chromatographic Science, Acta Chromatographica, Journal of Planar Chromatography, Current Chromatography, Current Medicinal Chemistry, Letters in Drug Design & Discovery, Medicinal Chemistry, Mini-Reviews in Medicinal Chemistry, The Open Medicinal Chemistry Journal, LC-GC Europe, LC-GC Asia-Pacific.


Department of Pharmacology and Pharmacotherapy
Semmelweis University

S.F. Malan (Biography
S.F. Malan

Sarel Malan obtained a Ph.D. in Pharmaceutical Chemistry, M.Sc. and B.Pharm. from the North-West University, Potchefstroom, South Africa. He is Professor and Director of the School of Pharmacy at the University of the Western Cape and is an Honorary Life Member of the Academy of Pharmaceutical Sciences and Fellow of the Pharmaceutical Society of South Africa. He has published more than 75 scientific papers and has authored or co-authored various papers and columns in professional journals, and conference contributions.


Department of Pharmaceutical Chemistry
School of Pharmacy
University of the Western Cape
South Africa

I. Niculescu-Duvaz (Biography
I. Niculescu-Duvaz

Dr. Ion Niculescu-Duvaz graduated at the Politechnical Institute in Bucharest, obtained a Ph.D. in Organic Chemistry (Cytostatic Hormones) at the Chemistry University ,Timisoara, Romania. He was the head of Anticancer Drug Department at the Oncological Institute in Bucharest and then the Head of Biochemistry Dept. at the same Institute.He was a holder of an Eleanor Roosevelt fellowship and moved in 1992, as senior scientist at The Institute of Cancer Research, Sutton, UK. He was also visiting Professor at the Faculty of Chemistry, in Le Mans, France.

He published142 scientific papers, 3 books, 13 chapters in monographies and authored 40 patents.


CRC Centre for Cancer Therapeutics
Institute of Cancer Research
CR-UK laboratories

K.M. Rahman (Biography
K.M. Rahman

Dr. Khondaker Miraz Rahman is a Senior Lecturer in Medicinal Chemistry in the Institute of Pharmaceutical Science (IPS), King’s College London. His research activities are focused on the application of synthetic medicinal chemistry and chemical biology techniques to the design, synthesis and evaluation of novel drug-like chemical scaffolds as anti-cancer and anti-infective agents. He is an inventor of 6 patents and has more than 10 years’ research experience in medicinal chemistry and lead optimization in the anti-cancer and anti-infective areas. He has experience in both early- and late-stage drug discovery and translational research; co-founding Transcriptogen Ltd in 2013 and Femtogenix Ltd in 2015.


Medicinal Chemistry
Institute of Pharmaceutical Science King’s College
United Kingdom

A. Serretti (Biography
A. Serretti

Alessandro Serretti MD, PhD, Associate Professor of Psychiatry at Bologna University, Italy. Coordinator of a research unit active in clinical and genetic studies of major psychoses.

Author of more than 500 scientific papers in peer reviewed journals, one textbook of psychiatry and over 600 presentations at meetings. H-Index of 77.Reviewer or member of the editorial board for 170 journals and funding agencies.


Department of Biomedical and NeuroMotor Science
University of Bologna
Institute of Psychiatry

O. Tabarrini (Biography
O. Tabarrini

Since 2002, associate Professor of Pharmaceutical Chemistry. The scientific activity, documented in 85 publications in international journals with high impact factors has been principally focused on the design and synthesis of small molecules as pharmacological tools and potential chemotherapeutic agents. She has a longstanding experience in the design and synthesis of heterocyclic compounds. The HIV represents her principle research interest but important results were recently achieved also in the anti-cytomegalovirus and anti-influenza fields, as well as derivatives as hepatitis C virus NS5B polymerase inhibitors. Other fields of interest are heterocyclic compounds as pump efflux inhibitors, and compounds active in Huntington disease.


Department of Pharmaceutical Sciences
University of Perugia

F. Yang (Biography
F. Yang

Prof. Feng Yang was associate researcher of Brookhaven national lab in USA after the phD in biophysics at graduate school of Chinese academy of sciences. Nowadays he is primary investigator of State Key Laboratory for the Chemistry and Molecular Engineering of Medicinal Resources. His research interests include design anticancer metal drug based on the protein structure, protein-based drug delivery systems, and multi-drug combination therapy of cancer. Prof. Feng Yang is the author of about 40 papers published in the peer reviewed international journals and he also reviewed several journals in the fields of medicinal chemistry.


Department of Chemistry and Pharmaceutical Science
Guangxi Normal University

J. Baranowska-Kortylewicz
Department of Radiation Oncology
Bruce Henriksen Cancer Research Laboratories
Omaha, NE

J. Chen
Department of Medicinal Chemistry
One Amgen Center Dr.
Thousand Oaks, CA

A. Copani
Department of Pharmaceutical Sciences
University of Catania

A. Gueiffier
Faculty of Pharmaceutical Sciences
University of Tours
Medicinal chemistry laboratory

Y. Ishikawa
Cardiovascular Research Institute
Yokohama City University
Graduate School of Medicine

C. Kerkhoff
Institute of Experimental Dermatology
University of Müenster

G. Kouraklis
Second Department of Propedeutic Surgery
University of Athens
School of Medicine

L.-J. Ming
Department of Chemistry
University of South Florida, Institute for Biomolecular Science
Tampa, FL

P. Perjesi
Department of Pharmaceutical Chemistry
University of Pecs
Institute of Pharmaceutical Chemistry

B. Pirotte
Department of Medicinal Chemistry
Pharmaceutical Chemistry Laboratory
University of Liege

S. Rapposelli
Department of Pharmaceutical Sciences
University of Pisa

T.J. Siahaan
Department of Pharmaceutical Chemistry
University of Kansas
Lawrence, KS

C.T. Supuran
Department Section of Pharmaceutical and Nutraceutical Sciences
University of Florence

J.A. Trapani
Cancer Cell Death and Killer Cell Biology Laboratories
Peter MacCallum Cancer Centre

J.S. Williamson
Department of Medicinal Chemistry
University of Mississippi
Oxford, MS

Associate Editorial Board Members:

N. Ahmed (Biography
N. Ahmed

Dr. Nafees has joined MONASH University Malaysia (MUM) in September 2012. He obtained M.S. (Pharm) and PhD in Natural Products chemistry/Medicinal Chemistry from National Institute of Pharmaceutical Education and Research (NIPER), Mohali, India. He worked on total synthesis of natural products, synthesis of new chemical analogues for discovery of new anti-HIV agents based on natural products templates. Before joining MUM as lecturer, he was a Postdoctoral Research Fellow in Department of Medicinal Chemistry, School of Pharmaceutical Sciences, Universiti Sains Malaysia (USM) Penang. His current areas are computational based rational design of new drug candidates for HIV-1, dengue and other therapeutics.


School of Pharmacy
Monash University- Malaysia Campus
Petaling Jaya

R.K. Singh (Biography
R.K. Singh

Dr. Rajesh Kumar Singh received his Bachelor (2003) and Master degree (2005) in Pharmacy from Panjab University, Chandigarh. He completed his PhD (2008-2013) in Pharmaceutical Chemistry from Punjab Technical University, Jalandhar, and is in teaching profession since 2003. Dr. Singh’s major area of research interests include drug-design, polymer-drug conjugates, CNS active therapeutic agents and green chemistry approaches for chemical synthesis. He has to his credit more than 40 Research Papers, 46 Conference Abstracts, 1 Book and 6 Best Paper Awards. He is currently Editorial Board Member of 04 International Journals, has reviewed more than 40 International papers and got 6 research grants funded by government agencies.


Pharmaceutical Chemistry Division
Shivalik College of Pharmacy Punjab Technical University (Jalandhar) Nangal Rupnagar

O.M. Ahmed (Biography
O.M. Ahmed

Dr. Osama M. Ahmed was granted Ph.D. (in 2000) in Physiology from Faculty of Science, Cairo University, Egypt. Dr. Ahmed is a professor of physiology at Faculty of Science, Beni-Suef University and Faculty of Oral and Dental Medicine, Nahda University, Beni-Suef, Egypt. His research interests are as follows: stem cell research, diabetes mellitus, maternal hypothyroidism and hyperthyroidism effects on fetuses and offspring, obesity, carcinogenesis, drug-induced toxicity, rheumatoid arthritis, hyperoxaluria, hyperhomocysteinemia, and assessment of medicinal plant and their constituents as well as novel synthetic organic compounds as protective, preventive and therapeutic remedies. He has authored/co-authored more than 90 publications, and has also written two book chapters.


Zoology Department
Beni-Suef University

J.K. Twibanire (Biography
J.K. Twibanire

Dr. Jean-d’Amour K. Twibanire received his Ph.D. (2013) in Chemistry from Dalhousie University, Halifax, Canada. He was awarded the prestigious Natural Sciences and Engineering Research Council of Canada (NSERC) Postdoctoral Fellowship, which he held at CanAm Bioresearch Inc. in Winnipeg, Canada, focusing mainly on Medicinal Chemistry. He has published several papers in International Chemistry Journals and has also published outside of chemistry, for example “The United Nations Security Council: Imbalance of Power and the Need for Reform” was published in The International Journal of Political Science and Diplomacy, which is open access. Currently, Dr. Twibanire is with CanAm Bioresearch Inc. in Winnipeg, Canada, as a Research Scientist and Investigator.


CanAm Bioresearch Inc


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