The Open Rheumatology Journal




ISSN: 1874-3129 ― Volume 13, 2019

Editor-in-Chief:

Xiaodong Zhou (Biography
Xiaodong Zhou

Dr. Xiaodong Zhou is a professor of Internal Medicine in the University of Texas Health Science Center at Houston. His major research interests include inflammation, fibrosis, genetics and autoimmunity in scleroderma, ankylosing spondylitis, rheumatoid arthritis, osteoarthritis and other rheumatic diseases. He holds editorial positions in multiple medical and translational journals.

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Department of Internal Medicine
University of Texas
Houston, TX
USA



Editorial Board Members:

N. Agmon-Levin (Biography
N. Agmon-Levin

Prof. Nancy Agmon- Levin is Head of the Clinical Immunology, Angioedema and Allergy Unit, Lupus and Autoimmune Diseases Clinic. She graduated from Hadassah Medical School, Hebrew University, Jerusalem and completed fellowship in Clinical Immunology at the German Cancer Research Center (DKFZ), Heidelberg, Germany. Prof. Agmon- Levin’s main field of interest are autoimmune diseases (lupus, antiphospholipid syndrome), immune system diseases (urticaria, angioedema, immune deficiency, Granulomatous Disease), immunotherapy, allergies in children and adults. She is a member in many professional societies and a co-author of numerous scientific articles.

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Lupus and Autoimmune Diseases Clinic
Sheba Medical Center
Ramat Gan
Israel

D. Bang (Biography
D. Bang

Dr. Dongsik Bang is a professor at the Department of Dermatology of Catholic Kwandong University International St. Mary’s Hospital, Incheon, South Korea. He was a professor at the Department of Dermatology of Yonsei University College of Medicine, Seoul, South Korea from 1984 to 2015. His major research is related with Behçet’s disease and diseases of the mucous membrane. He was Chief Editor of the Annals of Dermatology from 2007 to 2012.He published 263 papers and 9 books including Behçet’s Disease: A guide to its clinical understanding published by Springer Verlag Co., 2001 and Behçet’s Disease in Korea, 2013.

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Department of Dermatology
Catholic Kwandong University
Seoul
South Korea

N. de Vries (Biography
N. de Vries

Dr. N. de Vries is an associate professor in the Department of Clinical Immunology and Rheumatology, University of Amsterdam. He is a highly motivated and focused professional who operates as, clinician specialized in immunology & rheumatology, leader of a research team with focus on Genetics & Genomics in immune-mediated disease, teacher and director of the rheumatology training program at the AMC, experienced manager in academic health care. He published 228 paper in peer reviewed journals having Hirsch index 37.

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Department of Clinical Immunology and Rheumatology
Academic Medical Center/ University of Amsterdam
Amsterdam
Netherlands

S. Koarada (Biography
S. Koarada

Dr. Koarada is a doctorate (Ph.D. and M.D.) in Immunology from Saga University, Saga, Japan. He worked at UPMC (University of Pittsburgh Medical Center) (1999-2001) as an Associated Professor. Currently, Dr. Koarada is an Associated Professor of Saga University. His specialty is rheumatology and clinical immunology. He has published more than 100 scientific papers and 8 books. He has published the book series about imagings in rheumatology every year regularly.

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Division of Rheumatology
Saga University
Saga
Japan

A. Lo Gullo (Biography
A. Lo Gullo

Alberto Lo Gullo is a PhD student at University of Messina, Italy. He graduated at University of Messina and He is specialized in internal medicine. The main interest are Atherosclerosis and cardiovascular comorbidities in arthritis, biomarkers of endothelial damage, arterial stiffness, giant cell arteritis, polymyalgia rheumatica, vasculitis, periodontal involvement in systemic sclerosis. He is regular reviewer of international journals.

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Department of Clinical and Experimental Medicine
University of Messina
Messina
Italy

S.P. McKenna (Biography
S.P. McKenna

I have led a research group that has specialized in the development of patient reported outcome measures in a wide range of diseases (including rheumatology) for 30 years. Many of these measures are widely used in international clinical trials, in clinical practice, audit and by the National Health Service. Over this period I have become a leading international researcher in outcome measurement. We commonly work with research groups around the World to develop PROs in parallel or to adapt our measures for use in up to 70 additional languages. We are leaders in advancing methodology in PRO development and validation.

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Galen Research Limited
Manchester
UK

U. Muller-Ladner (Biography
U. Muller-Ladner

Prof. Müller-Ladner is Chair for Internal Medicine and Rheumatology at the Justus-Liebig University Giessen, Germany, and Director of the Department of Rheumatology and Clinical Immunology at the Kerckhoff-Clinic Bad Nauheim, Germany. Prior to this position, Prof. Müller-Ladner was Head of the Division of Rheumatology and Clinical Immunology at the University of Regensburg, Germany. Prof. Müller-Ladner is member of the Executive Committee of the German Society of Rheumatology and heading the German Competence Network for Rheumatology. He is also member of the Executive Committee of the EULAR Scleroderma Trials and Research Network (EUSTAR) and the German Network for Systemic Sclerosis.

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Department of Rheumatology and Clinical Immunology
Justus Liebig University
Giessen
Germany

M.T. Nurmohamed (Biography
M.T. Nurmohamed

Michael Nurmohamed is Rheumatologist and professor of Rheumatology at the VU University Medical Center, Amsterdam, The Netherlands. His chair has a focus on cardiovascular comorbidities in rheumatic diseases/vascular rheumatology. Furthermore, he is the Head of Rheumatology Research Dept. of Reade where he also works as Rheumatologist and Clinical Research Scientist since 2000. His main scientific interests include cardiovascular co-morbidities in rheumatic diseases. Dr. Nurmohamed has (co)authored over 200 publications in peer-reviewed journals and several book chapters, is a regular reviewer for several international journals and an editorial board member of Annals of Rheumatic Diseases , Arthritis Research Therapy, Journal of Rheumatology, The Open Rheumatology Journal and PlosOne. He serves on several (international) boards of cardiovascular scientific societies.

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Department of Rheumatology
VU University Medical Centre
Amsterdam
Netherlands

H. Tanaka (Biography
H. Tanaka

Dr. Hiroshi Tanaka obtained his M.D. status in 1989 from Hirosaki University, Japan. Moreover, he received Board certification in Pediatrics in 1992 and Board certification in Nephrology in 1997. Dr. Tanaka is currently Professor of School Health Science, Faculty of Education, Hirosaki University & Department of Pediatrics, Hirosaki University Hospital, Japan. He, as an author/co-author, has published over 140 articles in various journals, having total number of citations of more than 1,275. He has published mainly in in the subject areas of Biochemistry, Genetics, Molecular Biology, Immunology and Microbiology.

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Department of Pediatrics
Hirosaki University Hospital
Hirosaki
Japan

A.F. Wells (Biography
A.F. Wells

Dr. Alvin Francis Wells obtained his Ph.D. degree (1988) from University of South Carolina (School of Medicine – Department of Microbiology and Immunology), Columbia, SC, USA. Since May 2015, Dr. Wells currently holds the position of Director at Rheumatology and Immunotherapy Center, Franklin, WI, USA. His skills and expertise mainly lie in the subject areas of Biochemistry, Genetics, Molecular Biology, Immunology, Microbiology, Pharmacology, Toxicology, Pharmaceutics, Health Professions, etc. Dr. Wells, as an author/co-author, has published more than 30 articles in various journals, having over 825 total citations.

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Department of Internal Medicine
Duke University Medical Center
Durham, NC
USA

F. Ciccia (Biography
F. Ciccia

Dr. Francesco Ciccia obtained his Ph.D. degree (2008) from the University of Palermo (Medical School), Palermo, Italy. Since 2009, Dr. Ciccia is Assistant Professor of Rheumatology (in Dipartimento Biomedico di Medicina Interna e Specialistica) at University of Palermo. His skills and expertise mainly lie in the subject areas of Inflammation, Innate Immunity, Immunity, Cytokines, Adaptive Immunity, etc. Dr. Ciccia, as an author/co-author, has published more than 100 articles in various journals, having over 1,920 total citations.

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Department of Internal and Specialized Medicine
University of Palermo
Palermo
Italy

S. Vettori (Biography
S. Vettori

Dr. Serena Vettori is currently a Rheumatologist and Assistant Professor of Rheumatology at Università degli Studi della Campania “Luigi Vanvitelli”. She did MD fromthe “Seconda Universitá degli Studi di Napoli” in 2004 and Specialty in Rheumatology from the “Seconda Universitá degli Studi di Napoli” in 2009. In 2013, she did PhD in Clinical Physiopathology and Experimental Medicine from Università degli Studi di Napoli “Federico II”.

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Department of Internal and Experimental Medicine
University of Campania "Luigi Vanvitelli"
Naples
Italy

M. Atteritano (Biography
M. Atteritano

Dr. Marco Atteritano is currently a Research Fellow at University of Messina in Internal Medicine, Rheumatology and coordinator of project of research funded by the Italian Ministry of Health. He won several award in rheumatology field and internal medicine field. He is author of 50 peer-¬‐ reviewed papers with a personal H-factor of 15. His main fields of interest are the Rank-¬‐ Rankl-¬‐ OPG system in bone disease, Osteoporosis and metabolic bone disease, Ultrasound and DXA diagnostic of bone disease, Extraskeletal actions of vitamin d3, Genistein effects on skeleton and cardiovascular system in postmenopausal women, Rheumatic disease, Bone density in inflammatory bowel disease in children.

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Department of Internal Medicine-Rheumatology
University of Messina
Messina
Italy

I.M. Clark (Biography
I.M. Clark

Dr Clark is a biochemistry graduate, he undertook a PhD in the Rheumatology Research Unit in Addenbrooke’s Hospital. He won a Arthritis Research Campaign Copeman Fellowship to the USA where he began a project which led to the discovery of a cancer-associated SNP in the MMP1 gene. He returned to the Cambridge, UK on an Arthritis Research Campaign Postdoctoral Fellowship to develop his own interests. He is a molecular cell biologist with a research focus on (i) cartilage biology and osteoarthritis (OA) and (ii) Dupuytren’s disease. He is currently Professor of Musculoskeletal Biology at the University of East Anglia.

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School of Biological Sciences
University of East Anglia
Norwich
UK

N.G. Giordano (Biography
N.G. Giordano

Dr. Nicola Giuseppe Giordano graduated in Medicine from University of Siena (Italy) in 1974. He is a specialist in Rheumatology (1979) and in Immunology and Allergology (1982). He has been confirmed researcher with the qualification of Assistant Professor in the year 1979, first at the Siena University Rheumatology Institute, and later at the Internal Medicine Department of the University of Siena, where he still works. He is also author and co-author of works of Rheumatology and Internal Medicine as well as more than 200 issues, most of them printed on international literature, concerning etiopathogenetic, clinical and therapeutic aspects of some congenital and acquired diseases of the musculoskeletal system.

)

Department of Medicine
Surgery and Neuroscience
University of Siena
Siena
Italy

P.E. Lazzerini (Biography
P.E. Lazzerini

Pietro Enea Lazzerini is Assistant Professor of Medicine at the School of Medicine of the University of Siena, and a clinical internist at the University Medical Center “Policlinico Le Scotte” of Siena. He graduated from the same Institutions in 1997, where also completed his Internal Medicine residency. His research and clinical expertise are in immunologic and inflammatory mechanisms of cardiac arrhythmias and sudden death, cardiovascular involvement in systemic autoimmune diseases, pleiotropic effects of statins in rheumatology and immunology, homocysteine metabolism and purinergic system in inflammation and fibrogenesis.

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Department of Medical Sciences, Surgery and Neurosciences
University of Siena
Siena
Italy

A.A. Manfredi (Biography
A.A. Manfredi

Angelo Manfredi is Associate Professor of Rheumatology and Head of the Unit of Autoimmunity & Vascular Inflammation at the Università Vita Salute – San Raffaele Scientific Institute, Milano. He has been consistently working on the means by which intracellular antigens become immunogenic and on the mechanisms that have evolved to curb the initiation and persistence of inflammatory disease.

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Autoimmunity and Vascular Inflammation
San Raffaele Hospital
Milan
Italy

C. Montecucco (Biography
C. Montecucco

Dr. Carlomaurizio Montecucco, MD, is Full Professor of Rheumatology at University of Pavia since 2000. Currently, he is also affiliated with Policlinico S. Matteo Foundation and University of Brescia. His main fields of investigation are: (1) Biomarkers in Rheumatoid Arthritis, Systemic Sclerosis and Sjogren’s Syndrome; (2) Immunopathology, Chemokines and Lymphocyte Homing in Rheumatoid Arthritis; (3) Interventional Rheumatology (synovial biopsy, salivary gland biopsy, ultrasound guided procedures); and (4) Therapy of Rheumatoid Arthritis and Polymyaglia Rheumatica. Dr. Montecucco’s he has authored/co-authored more than 280 peer-reviewed papers.

)

Division of Rheumatology IRCCS
University of Pavia
Pavia
Italy

Y. Muro (Biography
Y. Muro

Dr. Yoshinao Muro, M.D., Ph.D., is currently working as an Associate Professor in the Department of Dermatology (Division of Connective Tissue Disease & Autoimmunity) at Nagoya University Graduate School of Medicine, Nagoya, Japan. Dr. Muro’s research interests mainly involve Immunology and Autoimmunity. Dr. Muro, as an author/co-author, has published more than 140 articles in various journals, having a significant number of total citations, i.e. over 3,325.

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Department of Dermatology
Nagoya University Graduate School of Medicine
Nagoya
Japan

K.P.H. Pritzker (Biography
K.P.H. Pritzker

Dr. Kenneth P. H. Pritzker, also known as Ken, M.D., FRCPC serves as the Chief Executive Officer and President at Proteocyte Diagnostics Inc. Dr. Pritzker serves as the Chief Innovation Officer of Rna Diagnostics Inc. Dr. Pritzker serves as the Managing Director of York Medtech Partners Inc. He serves as Professor, Laboratory Medicine and Pathobiology, Surgery at the University of Toronto. Dr. Pritzker served as the Chief Executive Officer of Rna Diagnostics Inc. With over 240 scientific publications, Dr. Pritzker is a recognized leader internationally in the fields of arthritis, biomaterials, genomics and nanotechnology.

)

Department of Laboratory Medicine and Pathobiology and Surgery
University of Toronto
Toronto
Canada

G. Valesini (Biography
G. Valesini

Professor Valesini after his medical degree and training at the Rome University “La Sapienza”, fulfilled a research fellowship at WHO Immunology Research and Training Center – Geneva (Switzerland) . He and his research group have developed new techniques for the detection of anti-phospholipid antibodies (aPL) and have carried out studies on the role of aPL in the pathogenesis of human diseases. He is also conducting research activities in rheumatoid arthritis, anti-CCP antibodies, systemic lupus erythematosus (SLE), neuro-SLE, anti-endothelial cell antibodies, Sjogren Syndrome and new treatment of autoimmune diseases with biological products. He has authored more than 400 articles and book chapters in international scientific journals. He serves on the editorial boards of several rheumatology journals.

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Dipartimento Medicina Interna e Specialità Mediche
La Sapienza Università di Roma
Rome
Italy

H. Zeidler (Biography
H. Zeidler

Prof. Dr.med. Henning Zeidler has an educational background in the areas of Internal Medicine, Rheumatology and Physical Medicine. Prof. Zeidler is Professor of Medicine and Rheumatology, Emeritus, at Medical School Hannover, Germany. Moreover, since 2007, he is in private rheumatological practice at Rheumatologikum Hannover. His research focus involves Follow-up of spondylarthropathy and reactive arthritis; Etiopathogenesis, clinical picture, diagnosis and treatment of Chlamydia-induced arthritis; Pharmaco-economics and health economics in rheumatoid arthritis; and Great artists and rheumatic diseases. Prof. Zeidler has authored/co-authored over 340 publications, having very noteworthy number of citations, i.e. more than 11,110.

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Division of Rheumatology
Hannover Medical School
Hannover
Germany

M. Tomcik (Biography
M. Tomcik

Michal Tomcik, MD, PhD, works at the Institute of Rheumatology in Prague, Czech Republic as a Rheumatologist, Assistant Professor, mentor of PhD students and a research group leader with focus on pathogenesis, animal models, biomarkers, atherosclerosis and non-pharmacological interventions in systemic sclerosis and myositis. He is a regular reviewer for international journals.

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Department of Rheumatology
University of Charles
Prague
Czech Republic


Associate Editorial Board Members:

D. Opris-Belinski (Biography
D. Opris-Belinski

Dr. Daniela Opris-Belinski, MD, PhD graduated in 2000 from Carol Davila University of Medicine and Pharmacy of Bucharest. Currently she is certified in both Rheumatology and Internal Medicine. In 2015, she became an Associate Professor at the same University. Her research interests include rheumatoid arthritis, systemic lupus, spondyloarthritis, Sjogen’s Syndrome and several forms of vasculitis. She has co-authored more than 80 papers in Rheumatology and Internal Medicine journals published a book and several book chapters.

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Department of Rheumatology
Sfanta Maria Hospital
Bucharest
Romania

M. Odeh (Biography
M. Odeh

Prof. Majed Odeh completed his M.D. in the Faculty of Medicine at the Technion – Israel Institute of Technology with the Prize of Excellence on his M.D. theses. He is the head of the Department of Internal Medicine A' at Bnai Zion Medical Center, Haifa, Israel, for more than eleven years, and serves as an associate professor of medicine at the Technion Faculty of Medicine. His main research interests include the role of tumor necrosis factor-α in the pathogenesis of various diseases, pathogenesis of hepatic encephalopathy, pleural diseases, obstructive sleep apnea, specific topics in rheumatology, and adverse drug reactions. Prof. Odeh has published more than 200 papers of basic and clinical research in international peer-reviewed medical and physiological journals. He is a permanent distinguished lecturer in medical education and teaching at the Technion Faculty of Medicine for more than 25 years. He is also a winner of more than 38 prizes and awards in basic and clinical research, and medical education and teaching. Prof. Odeh is the winner of Ig Noble Prize in the field of Medicine for the year 2006. He served and is serving as an Editorial Board Member or Reviewer of more than 43 international medical journals.

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Department of Internal Medicine A
Bnai Zion Medical Center
Haifa
Israel

M.N. Sahib (Biography
M.N. Sahib

Dr. Mohanad received his B.S. in Pharmaceutical Sciences and MSc. in Pharmaceutics from College of Pharmacy, Baghdad University, Baghdad, Iraq in 1999 and 2006, respectively. He received his Ph.D. degree in Pharmaceutical Technology from School of Pharmaceutical Sciences, Universiti Sains Malaysia in 2012. He was formerly worked as an Assistant Professor at Universiti Sains Malaysia and currently he is a Lecturer in the Faculty of Pharmacy, Al-Rafidain University College, Baghdad, Iraq. His interdisciplinary research focuses on osteoporosis and related problems, improve pharmacy practice, quality of life and management of chronic diseases. Moreover, formulation and characterization of drug delivery system.

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Faculty of Pharmacy
Al-Rafidain University College
Baghdad
Iraq

F. Frikha (Biography
F. Frikha

Dr. Faten FRIKHA is an Associate Professor of internal Medicine at the Department of Internal Medicine, Sfax TUNISIA. She is the author of over 60 articles. She has : 1- Diplôma of manual theray (osteopathy and physiotherapy) and spinal diseases 2- Diplôma of « Rheumatology and systemic diseases ». 3- Diplôma of « sexology” ; 4- Diplôma of « Osteoporosis and bone diseases » 5- Diplôma of « Hypertension, cardio-vascular and renal diseases » 6- Diplôma of « Dermatology and systemic diseases » 7- Diplôma of « Immunotherapy and biologic drugs in inflammatory ad auto-immune diseases ».

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Department of Internal Medicine
Hedi Chaker University Hospital
Sfax
Tunisia

S. Parisi (Biography
S. Parisi

Dr. Simone Parisi obtained his Degree in Medicine and Surgery in 2006 from University of Turin, Italy. Since May 2015, Dr. Parisi is a Rheumatologist at Azienda Ospedaliero Universitaria Città Della Salute e della Scienza di Torino (University Hospital of Health and Science in Turin). In addition, since March 2007, he is a Consultant of the Institute of Sports Medicine (FMSI) of Turin. His skills and expertise mainly lie in the subject areas of Osteoarticular Ultrasonography, Videocapillaroscopy, Ultrasound Guided Joint Injection, Non Transfusional Hemo-Components (Platelet Rich Factor), Inflammation, Innate Immunity, Autoimmunity, Osteoporosis, Immune Regulation, Osteoarthritis, Rheumatic Diseases, etc. Dr. Parisi, as an author/co-author, has published more than 30 articles in various journals.

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Department of Rheumatology
University Hospital of Health and Science
Turin
Italy












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