Bioactive Alkaloids from South American Psychotria and Related Species
Diogo D. Porto1, Amélia T. Henriques2, Arthur G. Fett-Neto1, 3, *
1 Centro de Biotecnologia, Universidade Federal do Rio Grande do Sul, Brazil
2 Faculdade de Farmácia, Universidade Federal do Rio Grande do Sul, Brazil
3 Departamento de Botânica, Universidade Federal do Rio Grande do Sul, Brazil
Many important molecules have been discovered from tropical and sub-tropical plant biodiversity. However, the largest part of the chemical profile of such biodiversity remains unknown. Combining ethnopharmacological and chemotaxonomical investigation can be a good strategy in bioactive compound discovery. South American Psychotria species studied by this approach proved to be a rich source of new bioactive alkaloids, some of which bear unique chemical skeletons.
Key Words: Alkaloids, South America, Psychotria, Ethnopharmacology, Analgesic.
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* Address correspondence to this author at the Center for Biotechnology, Federal University of Rio Grande do Sul, P.O Box 15005, Porto Alegre, RS, Brazil, Postal Code: 91501-970, Brazil; Tel: 55 51 3308 7642; Fax: 55 51 3308 7309;