The Open Bioactive Compounds Journal


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Bioactive Alkaloids from South American Psychotria and Related Species

Diogo D. Porto1, Amélia T. Henriques2, Arthur G. Fett-Neto1, 3, *
1 Centro de Biotecnologia, Universidade Federal do Rio Grande do Sul, Brazil
2 Faculdade de Farmácia, Universidade Federal do Rio Grande do Sul, Brazil
3 Departamento de Botânica, Universidade Federal do Rio Grande do Sul, Brazil


Many important molecules have been discovered from tropical and sub-tropical plant biodiversity. However, the largest part of the chemical profile of such biodiversity remains unknown. Combining ethnopharmacological and chemotaxonomical investigation can be a good strategy in bioactive compound discovery. South American Psychotria species studied by this approach proved to be a rich source of new bioactive alkaloids, some of which bear unique chemical skeletons.

Key Words: Alkaloids, South America, Psychotria, Ethnopharmacology, Analgesic.

Article Information

Identifiers and Pagination:

Year: 2009
Volume: 2
First Page: 29
Last Page: 36
Publisher Id: TOBCJ-2-29
DOI: 10.2174/1874847300902010029

Article History:

Received Date: 3/5/2009
Revision Received Date: 15/5/2009
Acceptance Date: 20/5/2009
Electronic publication date: 15 /9/2009
Collection year: 2011

© Porto et al.; Licensee Bentham Open.

open-access license: This is an open access article licensed under the terms of the Creative Commons Attribution Non-Commercial License ( which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.

* Address correspondence to this author at the Center for Biotechnology, Federal University of Rio Grande do Sul, P.O Box 15005, Porto Alegre, RS, Brazil, Postal Code: 91501-970, Brazil; Tel: 55 51 3308 7642; Fax: 55 51 3308 7309; E-mail:

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