1 Department of Chemistry, Faculty of Mathematics and Natural Sciences, Padjadjaran University, Jatinangor 45363,
2 Department of Biology, Faculty of Mathematics and Natural Sciences, Padjadjaran University,
Jatinangor 45363, Sumedang, Indonesia;
3 Division of Applied Life Sciences, Graduate School of Life and
Environmental Sciences, Osaka Prefecture University, Gakuen-cho, Sakai, Osaka 599-8531, Japan
Flavonoids compounds such as kaempferol (1), kaempferol-3-O-β-D-glucopyranoside or astragalin (2) and
kaempferol-3-O-α-L-rhamnoside or afzelin (3) have been isolated from the fresh leaves of Kalanchoe tomentosa
(Crassulaceae). The chemical structure of isolated compounds 1-3 were identified by spectroscopic evidences and
comparison with those compound previously reported. Compounds 1-3 showed cytotoxic activity against P-388 murine
leukimia cells with IC50 values of 51.8, > 100 and 3.32 µg/mL, respectively.
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