The Open Biochemistry Journal




ISSN: 1874-091X ― Volume 13, 2019
RESEARCH ARTICLE

Effects of Glucan and Vitamin D Supplementation on Obesity and Lipid Metabolism in Diabetic Retinopathy



Martina Závorková1, Vaclav Vetvicka2, *, Josef Richter3, Vlastimil Kral3, Ivana Liehnova1, Dobiasova L. Rajnohova3
1 Official Clinic of UJEP Masaryk Hospital, Regional Health, Usti and Labem, Czech Republic
2 University of Louisville, Department of Pathology, Louisville, KY, USA
3 Health Institute with headquarters in Usti and Labem, Usti and Labem, Czech Republic

Abstract

Background:

Diabetes mellitus is a chronic disease manifested by an increase of blood glucose.

Objective:

To evaluate the effects of glucan and vitamin D supplementation in patients with diabetic retinopathy.

Method:

We evaluated the effects of 3-month supplementation with glucan and vitamin D in 54 patients with diabetic retinopathy. We measured levels of vitamin D, cholesterol, HDL cholesterol, and triglycerides.

Results:

The supplementation strongly decreased the cholesterol levels and improved the levels of HDL cholesterol. In addition, vitamin D levels were strongly improved, but still not at optimal values.

Conclusion:

From our data, we concluded that glucan and vitamin D supplementation strongly influence lipid metabolism and have positive effects on human health.

Keywords: Glucan, Vitamin D, Diabetes, Obesity, Diabetic retinopathy, Supplementation, Clinical trials.


Article Information


Identifiers and Pagination:

Year: 2018
Volume: 12
First Page: 36
Last Page: 45
Publisher Id: TOBIOCJ-12-36
DOI: 10.2174/1874091X01812010036

Article History:

Received Date: 23/11/2017
Revision Received Date: 19/03/2018
Acceptance Date: 22/03/2018
Electronic publication date: 30/03/2018
Collection year: 2018

Article Metrics:

CrossRef Citations:
0

Total Statistics:

Full-Text HTML Views: 1524
Abstract HTML Views: 796
PDF Downloads: 1044
ePub Downloads: 743
Total Views/Downloads: 4107

Unique Statistics:

Full-Text HTML Views: 916
Abstract HTML Views: 409
PDF Downloads: 393
ePub Downloads: 249
Total Views/Downloads: 1967
Geographical View

© 2018 Závorková et al.

open-access license: This is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International Public License (CC-BY 4.0), a copy of which is available at: (https://creativecommons.org/licenses/by/4.0/legalcode). This license permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.


* Address correspondence to this author at the Department of Pathology, University of Louisville, Vaclav Vetvicka, 511 S. Floyd, Louisville, KY 40202, USA; Tel: 5028521612; E-mail: vaclav.vetickalouisville.edu


Endorsements



"We have always had a fruitful cooperation and long-term experience of publishing with Bentham Open."

"A number of our original papers have appeared in its different journals, as the Bentham Open Publishers provides sufficient research in the field of science and technologies (belonging to the pharmaceutical, biotechnology, biomedical industries etc). The staff of the Bentham Open always treat our papers very seriously and gently during the rutile paper reviewing process, so far we always felt their kindness and highly cooperative support. Today, Bentham Open is providing a great support to science and research, giving opportunities of high standard publishing as well as promoting and enhancing selected papers around the world through communication and exchange of global scientific education."


Kholmirzo T. Kholmurodov
Leading Scientist
FLNP (Frank Laboratory of Neutron Physics) JINR (Joint Institute of Nuclear Research) Moscow region, Russia


Browse Contents



Webmaster Contact: info@benthamopen.net
Copyright © 2019 Bentham Open