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Microfluidic micromixers are extremely essential components of microfluidic systems for microliter to nanoliter
fluid mixing. This paper proposes a new passive micromixer called the self-vortical micromixer with no obstructions,
composed of three polydimethylsiloxane (PDMS) layers. Each PDMS layer is fabricated by a PDMS replication molding
process with a 150-micron height dry-film photoresist replication mold, manufactured from an organic solvent-free process.
The three PDMS layers are precisely bonded together by the PDMS alignment bonding process developed in this
study. This paper presents the simulation results demonstrating the self-vortical mixing phenomenon of the self-vortical
micromixer with swirly flow fields and self-vortical flow fields. As the mixing test results demonstrate the mixing performance
of the micromixer, the injected food dyes are completely mixed in the downstream of the mixing channel by the
swirly flow fields and the self-vortical flow fields in the circular mixing chamber of the self-vortical micromixer. At Re
=200, effective mixing (mixing index 0.42) can be achieved..