REVIEW ARTICLE


Donor-recipient Matching in Heart Transplantation



Aleksandra Oprzędkiewicz1, Hubert Mado1, *, Wioletta Szczurek2, Mariusz Gąsior3, Bożena Szyguła-Jurkiewicz3
1 Student Scientific Society, 3rd Department of Cardiology, School of Medical Sciences in Zabrze, Medical University of Silesia, Katowice, Poland
2 Silesian Center for Heart Diseases in Zabrze, Poland
3 3rd Department of Cardiology, School of Medical Sciences in Zabrze, Medical University of Silesia, Katowice, Poland


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Creative Commons License
© 2020 Oprzędkiewicz et al.

open-access license: This is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International Public License (CC-BY 4.0), a copy of which is available at: https://creativecommons.org/licenses/by/4.0/legalcode. This license permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

* Address correspondence to this author at Student Scientific Society, 3rd Department of Cardiology, School of Medical Sciences in Zabrze, Medical University of Silesia, Katowice, Poland; Tel: +48694138970; +48695948463; E-mail: hubert.mado@med.sum.edu.pl


Abstract

Heart transplantation remains the treatment of choice for end-stage Heart Failure (HF). Due to the shortage of organs for transplantation and the occurrence of perioperative complications, a key problem is donor matching, which should result in increased survival and improved quality of life for patients. The success of this procedure depends on various parameters such as gender, weight, ABO blood group and Human Leukocyte Antigen (HLA) system of both the recipient and the donor. Furthermore, non-HLA antigens may also be valuable in donor-recipient matching. The aim of this article is to summarize the recent knowledge on the impact of various factors on accurate donor-recipient matching to heart transplantation.

Keywords: Heart failure, Heart transplant, Donor-recipient matching, Non-HLA, Chronic graft vasculopathy, Ventricular assist device.