The Properties of Poly (Acrylic Acid) Modified with N-Phenylbenzothioamide
as Potential Drug Carriers
Halina Kaczmarek*, Magdalena MetzlerFaculty of Chemistry, Nicolaus Copernicus University, 7, Gagarin Str., 87-100 Toruń, Poland
Abstract
Poly(acrylic acid) and N-phenylbenzothioamide have been synthesized under laboratory conditions. The purity
of products has been checked by FTIR and NMR spectroscopy. The obtained N-phenylbenzothioamide has been used for
modification of poly(acrylic acid) properties. The prepared blend of PAA contained small amout of dopant (1-5 wt %).
Thermal and photochemical stability of obtained specimens were investigated using UV-Vis spectroscopy and
thermogravimetric analysis. Crosslinking yield was estimated by extraction of insoluble gel formed. It was found that N-phenylbenzothioamide
stabilizes poly(acrylic acid) during UV-irradiation which is explained by efficient crosslinking
reaction.
Keywords: : Crosslinking, N-phenylbenzothioamide, photochemical stability, poly(acrylic acid), thermal stability.
Article Information
Article History:
Received Date: 4/8/2013
Revision Received Date: 19/12/2013
Acceptance Date: 20/12/2013
Electronic publication date: 21/2/2014
Collection year: 2014
© Kaczmarek and Metzler; Licensee Bentham Open.
open-access license: This is an open access article licensed under the terms of the Creative Commons Attribution Non-Commercial License (
http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.
* Address correspondence to this author at the Faculty of Chemistry,
Nicolaus Copernicus University, 7, Gagarin Str., 87-100 Toruń, Poland;
Tel: (48 56) 611 43 12; Fax: (48 56) 654 24 77;
E-mail: halina@chem.uni.torun.pl
Open Peer Review Details |
Manuscript submitted on 4-8-2013 |
Original Manuscript |
The Properties of Poly (Acrylic Acid) Modified with N-Phenylbenzothioamide
as Potential Drug Carriers |