In this paper, we propose a novel region-based active contour model in a variational level set formulation. The
energy functional for the proposed model consists of two terms, i.e., global term, local term. Therefore, the combination
of these two forces allows for flexible initialization of the contours. This energy is then incorporated into a level set formulation
with a level set regularization term that is necessary for accurate computation in the corresponding level set
method. The proposed model is first presented as a two-phase level set formulation and then extended to a multi-phase
formulation. Finally, experiments on some synthetic and real images have demonstrated the efficiency and robustness of
our model. Moreover, comparisons with recent popular local image fitting (LIF) model also show that our model is less
sensitive to the location of initial contour.