Open Longevity Science




(Discontinued)

ISSN: 1876-326X ― Volume 7, 2013

Karnofsky Performance Scale and Mini Nutritional Assessment Predict Mortality in Geriatric Patients


Open Longevity Science, 2008, 2: 17-22

Sandra Hirsch, Ana Maria Salazar, M Pía de la Maza, Ana Maria Molina, Andres Navarrete, Lidia Lera, Gladys Barrera, Vivien Gattas , Daniel Bunout

INTA, University of Chile, PO Box 138-11, Santiago, Chile.

Electronic publication date 09/5/2008
[DOI: 10.2174/1876326X00802010017]

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Abstract:

Morbidity and mortality in elderly patients admitted to hospital are high. Prognostic information collected at hospital admission is useful to define care objectives for older people.

Aim:

to compare the ability of the Mini Nutritional assessment (MNA) and the Karnofsky Performance Score (KS) to predict mortality in hospitalized geriatric patients.

Methods:

A prospective 9 -months follow-up study was designed. One hundred thirteen subjects aged 65 years or more, admitted consecutively over 6 months to a Medicine guard of a Military Hospital in Santiago, Chile, were included. Upon admission, patients underwent a medical history and examination. MNA and KS were measured. Mortality data during the 9 months after inclusion in the study were obtained from the Chilean population records at the “Registro Civil de Chile”.

Results:

Thirty-six patients (32%) died during the follow-up period. According to ROC curves the cut off point for MNA was 17 and 30 for KS (area under ROC curve=0.79 and 0.81). The Kaplan –Meier curves showed that survival rate in the group with KS ≤ 30 was 31% and 80% in those with >30. For MNA ≤ 17, survival rate was 47% and 72% with >17. In multiple step-wise logistic regression analysis, KS and MNA were independent predictors of mortality. However when mortality OR for MNA were adjusted for KS, the former lost its predictive capacity.

Conclusions:

KS ≤ 30 in geriatric patients is a better predictor of mortality than MNA and it can be recommended as a routine assessment in geriatric hospitalized patients. However MNA is useful to decide the use of nutritional support measures that could facilitate prognosis of a given patient.


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