The Open Mycology Journal




(Discontinued)

ISSN: 1874-4370 ― Volume 8, 2014

Chemoattractive Mechanisms in Filamentous Fungi


The Open Mycology Journal, 2014, 8: 28-57

Alexander Lichius, Kathryn M. Lord

Institute of Chemical Engineering, Vienna University of Technology, Austria.

Electronic publication date 11/July/2014
[DOI: 10.2174/1874437001408010028]

CrossRef Citations:
0


Article Metrics:

Geographical View
Total Statistics:

Abstract HTML Views: 338
PDF Downloads: 143
Total Views/Downloads: 481

Unique Statistics:

Abstract HTML Views: 242
PDF Downloads: 128
Total Views/Downloads: 370


Abstract:

Research on cell communication and differentiation in filamentous fungi has provided a number of novel insights into chemoattractive mechanisms in recent years. Still, identification of specific chemoattractant molecules, cognate receptors and downstream signaling pathways is strongly biased towards those involved in mating; probably due to the relative ease of functional genomic comparison to the budding yeast model. The multicellular nature of filamentous fungi, however, preserved a more complex morphology compared to unicellular fungi and revealed chemoattractive mechanisms lost during yeast evolution. Two hallmarks of this higher complexity are the formation of an interconnected colony network and the development of elaborate sexual reproductive organs. Morphogenesis of both structures depends on two different modes of chemoattraction: attraction to self and attraction to nonself. Nonself chemoattraction between genetically distinct mating partners is the basis for sexual reproduction and generally regulated through a bilateral sexpheromone/ cognate-receptor system, widely but not exclusively equivalent to that known from yeasts. In contrast, selfchemoattraction between genetically identical cells is regulated independently of the sex-pheromone/cognate-receptor systems, and does not exist in yeast. Although both chemoattractive modes do share a number of molecular components, we are only beginning to understand how cell morphogenesis is regulated by means of gene expression and targeted protein recruitment during the establishment of self-fusion. This review provides an overview on the main morphogenetic elements involved in fungal chemoattraction, and summarizes our current understanding of the underlying molecular mechanisms of self- and nonself-fusion during filamentous fungal development.


Download PDF

Endorsements



"Open access will revolutionize 21st century knowledge work and accelerate the diffusion of ideas and evidence that support just in time learning and the evolution of thinking in a number of disciplines."


Daniel Pesut
(Indiana University School of Nursing, USA)

"It is important that students and researchers from all over the world can have easy access to relevant, high-standard and timely scientific information. This is exactly what Open Access Journals provide and this is the reason why I support this endeavor."


Jacques Descotes
(Centre Antipoison-Centre de Pharmacovigilance, France)

"Publishing research articles is the key for future scientific progress. Open Access publishing is therefore of utmost importance for wider dissemination of information, and will help serving the best interest of the scientific community."


Patrice Talaga
(UCB S.A., Belgium)

"Open access journals are a novel concept in the medical literature. They offer accessible information to a wide variety of individuals, including physicians, medical students, clinical investigators, and the general public. They are an outstanding source of medical and scientific information."


Jeffrey M. Weinberg
(St. Luke's-Roosevelt Hospital Center, USA)

"Open access journals are extremely useful for graduate students, investigators and all other interested persons to read important scientific articles and subscribe scientific journals. Indeed, the research articles span a wide range of area and of high quality. This is specially a must for researchers belonging to institutions with limited library facility and funding to subscribe scientific journals."


Debomoy K. Lahiri
(Indiana University School of Medicine, USA)

"Open access journals represent a major break-through in publishing. They provide easy access to the latest research on a wide variety of issues. Relevant and timely articles are made available in a fraction of the time taken by more conventional publishers. Articles are of uniformly high quality and written by the world's leading authorities."


Robert Looney
(Naval Postgraduate School, USA)

"Open access journals have transformed the way scientific data is published and disseminated: particularly, whilst ensuring a high quality standard and transparency in the editorial process, they have increased the access to the scientific literature by those researchers that have limited library support or that are working on small budgets."


Richard Reithinger
(Westat, USA)

"Not only do open access journals greatly improve the access to high quality information for scientists in the developing world, it also provides extra exposure for our papers."


J. Ferwerda
(University of Oxford, UK)

"Open Access 'Chemistry' Journals allow the dissemination of knowledge at your finger tips without paying for the scientific content."


Sean L. Kitson
(Almac Sciences, Northern Ireland)

"In principle, all scientific journals should have open access, as should be science itself. Open access journals are very helpful for students, researchers and the general public including people from institutions which do not have library or cannot afford to subscribe scientific journals. The articles are high standard and cover a wide area."


Hubert Wolterbeek
(Delft University of Technology, The Netherlands)

"The widest possible diffusion of information is critical for the advancement of science. In this perspective, open access journals are instrumental in fostering researches and achievements."


Alessandro Laviano
(Sapienza - University of Rome, Italy)

"Open access journals are very useful for all scientists as they can have quick information in the different fields of science."


Philippe Hernigou
(Paris University, France)

"There are many scientists who can not afford the rather expensive subscriptions to scientific journals. Open access journals offer a good alternative for free access to good quality scientific information."


Fidel Toldrá
(Instituto de Agroquimica y Tecnologia de Alimentos, Spain)

"Open access journals have become a fundamental tool for students, researchers, patients and the general public. Many people from institutions which do not have library or cannot afford to subscribe scientific journals benefit of them on a daily basis. The articles are among the best and cover most scientific areas."


M. Bendandi
(University Clinic of Navarre, Spain)

"These journals provide researchers with a platform for rapid, open access scientific communication. The articles are of high quality and broad scope."


Peter Chiba
(University of Vienna, Austria)

"Open access journals are probably one of the most important contributions to promote and diffuse science worldwide."


Jaime Sampaio
(University of Trás-os-Montes e Alto Douro, Portugal)

"Open access journals make up a new and rather revolutionary way to scientific publication. This option opens several quite interesting possibilities to disseminate openly and freely new knowledge and even to facilitate interpersonal communication among scientists."


Eduardo A. Castro
(INIFTA, Argentina)

"Open access journals are freely available online throughout the world, for you to read, download, copy, distribute, and use. The articles published in the open access journals are high quality and cover a wide range of fields."


Kenji Hashimoto
(Chiba University, Japan)

"Open Access journals offer an innovative and efficient way of publication for academics and professionals in a wide range of disciplines. The papers published are of high quality after rigorous peer review and they are Indexed in: major international databases. I read Open Access journals to keep abreast of the recent development in my field of study."


Daniel Shek
(Chinese University of Hong Kong, Hong Kong)

"It is a modern trend for publishers to establish open access journals. Researchers, faculty members, and students will be greatly benefited by the new journals of Bentham Science Publishers Ltd. in this category."


Jih Ru Hwu
(National Central University, Taiwan)


Browse Contents



Webmaster Contact: info@benthamopen.net
Copyright © 2019 Bentham Open