The Renuva™ System is a dietary supplement sold to prevent symptoms of age-related growth
Test the ability of the Renuva™ System to increase growth hormone (GH) and insulin-like growth factor-1
The Renuva™ System is a two-part dietary supplement to maintain a healthy endocrine system. The “Generator
Drink” contains amino acids and nicotinic acid. The “Infuser Spray” contains growth hormone releasing peptides in a patented
oral delivery system. The Renuva™ System was given to 13 healthy volunteers >40 years. Two of 13 subjects were
given just the “Infuser Spray” to swallow, and four subjects were given just the “Generator Drink” on a second occasion.
GH and IGF-1 were measured at -10, -5, 0, 30, 60, 90, 120, and 180 minutes.
Thirteen subjects receiving the two-part Renuva™ System increased GH 98 + 50.2% (SEM) (p<0.05) from baseline,
and IGF-1 rose 35.8 + 45.0 ng/mL (p<0.02) from baseline at 120 minutes. Average IGF-1 levels of 2 subjects receiving
just the “Infuser Spray” was less 174.8 + 20.8 ng/ml) than average IGF-1 post-baseline values during the test using
both the Infuser Spray and Generator drink (213 + 37.2 ng/mL, p<0.002). Average IGF-1 levels of 4 subjects receiving
just the “Generator Drink” was less (202.6 + 124.7 ng/mL) than average IGF-1 post-baseline values when using both the
Infuser spray and the Generator drink (234.8 + 32.2 ng/mL, p=NS).
The Renuva™ System increases GH and IGF-1. Both the Generator Drink and the Infuser Spray appear to
contribute to the increase in IGF-1.