The Open Ophthalmology Journal




ISSN: 1874-3641 ― Volume 13, 2019
RESEARCH ARTICLE

The Effect Of Topical Antihistamines Used Single Dose Daily in Allergic Conjunctivitis



Hakika Erdogan*, Ozlem Cam
Department of Medicine, Faculty of Ophthalmology, Maltepe Unıversity, Maltepe, Istanbul, Turkey

Abstract

Background and Objective:

To evaluate the efficacy of 0.2% olopatadine and to compare olopatadine 0.1%, ketotifen 0.025% and emadastine 0.05% in the treatment of allergic conjunctivitis.

Methods:

In this retrospectively designed study, we investigated the files of patients who had been diagnosed with perineal or seasonal allergic conjunctivitis in the teaching hospital of Maltepe University between April 2017 and July 2017. We divided the patients into four groups. The patients in each group had similar symptoms and scores before medication. The first, second, third and fourth groups were prescribed olapatadine 0.1%, olopatadine 0.2%, ketotifen 0.025% and emedastine 0.05%, respectively. We evaluated the symptoms and signs of the patients on the 15th day after treatment, and compared the results between the groups.

Results:

We investigated the files of 80 patients. There were 20 patients in each group. We evaluated the symptoms and finding scores after treatment. The symptoms and findings of allergic conjunctivitis had improved in all the four groups. There was no difference in the treatment responses between the four groups.

Conclusion:

Olopatadine 0.2%, olopatadine 0.1%, ketotifen 0.025% and emedastine 0.05% were all equally effective in improving the signs and symptoms of allergic conjunctivitis.

Keywords: Allergic conjunctivitis, Antihistamines, Mast cell stabilization, Olopatadine, Ketotifen, Emedastine.


Article Information


Identifiers and Pagination:

Year: 2018
Volume: 12
First Page: 330
Last Page: 337
Publisher Id: TOOPHTJ-12-330
DOI: 10.2174/1874364101812010330

Article History:

Received Date: 19/10/2018
Revision Received Date: 30/11/2018
Acceptance Date: 03/12/2018
Electronic publication date: 31/12/2018
Collection year: 2018

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© 2018 Erdogan and Cam.

open-access license: This is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International Public License (CC-BY 4.0), a copy of which is available at: (https://creativecommons.org/licenses/by/4.0/legalcode). This license permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.


* Address correspondence to this author at the Department of Medicine, Faculty of Ophthalmology, Maltepe Unıversity, Maltepe, Istanbul, Turkey; Tel: +90 505 872 65 52; E-mail: dr.gercek@yahoo.com


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