CASE REPORT


Infective Keratitis Following Iontophoresis-assisted Corneal Crosslinking (I-CXL): A Case Report



Noor M. Alqudah1, *, Hisham M. Jammal1
1 Department of Ophthalmology, Faculty of Medicine, Jordan University of Science and Technology, Irbid, Jordan


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Creative Commons License
© 2021 Alqudah and Jammal

open-access license: This is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International Public License (CC-BY 4.0), a copy of which is available at: https://creativecommons.org/licenses/by/4.0/legalcode. This license permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

* Address correspondence to this author at the Department of Ophthalmology, Faculty of Medicine, Jordan University of Science and Technology, PO Box 3030 Ramtha Street, Irbid, 22110 Irbid, Jordan; E-mail: nmalqudah5@just.edu.jo


Abstract

Introduction:

The standard corneal crosslinking (S- CXL) technique requires corneal epithelial removal, thus increasing the risk of postoperative complications. Newer technique like iontophoresis-assisted corneal crosslinking (I-CXL) with comparable efficacy as S-CXL but without the increased risk of complications associated with corneal epithelium removal is used. However, being a comparatively newer technique, the safety and efficacy of I-CXL have not been fully explored.

Case Description:

Here, we present a case of a 28-year-old woman who presented with infective keratitis in one eye after uneventful bilateral I-CXL for keratoconus. Two days after the procedure, the patient presented with decreased vision and pain in the right eye. Clinical examination revealed ciliary injection and central corneal rounded infiltrates measuring 3.0 mm × 3.0 mm with an overlying epithelial defect. Microbiological studies revealed negative results. Based on clinical examination, the patient was managed successfully with fortified topical antibiotics.

Conclusion:

To the best of our knowledge, we report the first documented case of unilateral infective keratitis following bilateral I-CXL. Ophthalmologists should monitor the possible complications post-I-CXL as it might not be as safe as we expect.

Keywords: Corneal crosslinking, Culture-negative keratitis, Infective keratitis, Iontophoresis assisted corneal crosslinking, Efficacy, Ciliary injection.