This paper discusses the current problems of assessing the pipeline integrity from an identification of the causal factors associated to various pipeline failure mechanisms and damages, such as corrosion, SCC, buckling, soil movement, and fatigue. The paper explains, furthermore, how emerging applications of Neutron Diffraction and Small Angle Neutron Scattering techniques can be carried out to assess residual stress and microstructural characterization in pipelines. The benefits of the mentioned techniques are also discussed, in determining the pipeline real conditions and building forecast fracture models, providing end-users with essential support to effectively manage pipeline rehabilitation and maintenance plans.