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Purpose: Cherry laurel has been used as an anti-diabetic drug. In this study, we aimed to evaluate its antidiabetic
activity at standard living conditions and under stress by an experimental study.
Material and Method: Forty Wistar-Albino rats weighing 300–350 grams were used in this study. Four groups were
structured: control, diabetic, glibenclamide and cherry laurel extract. Streptozotocin (50 mg/kg) was injected to induce
diabetes. Cherry laurel extract was obtained from the seed of the fruit. Routine blood glucose, insulin, pre- and intraanesthesia
blood glucose levels were measured and compared. The One-way ANOVA followed by Duncan post-hoc test
was used for statistical analysis.
Results: After the second week of the experiment, Extract 300 and Extract 600 groups had the lower glucose levels
(p<0.05). Also, insulin levels measured at the last week of the study revealed that Extract 300 and Extract 600 groups had
the highest results (p< 0.01). Glucose levels under stress conditions significantly changed for Extract 300 and
glibenclamide group (p<0.05). Glucose level changed more obviously in the Extract 600 group (p<0.001) that means
Conclusion: Cherry laurel extract exhibits an anti-diabetic effect, with administration leading to elevated insulin levels,
and regulating glucose levels under stress conditions like anesthesia. These preliminary results indicate that further
evaluation is warranted.