Four compounds were isolated from the ethyl acetate crude extract of Xestospongia sp., namely benzoic acid, 2-phenylacetic
acid, 2-hydroxyl-1H-inden-1-one and 6-styryl-5,6-dihydropyran-2-one. The structures of these compounds were elucidated
based on spectroscopic methods including nuclear magnetic resonance (NMR-1D and 2D), UV, IR, mass spectrometry and
comparison with literature data. The ethyl acetate extract showed weak antityrosinase and acethylcholinasterase activities.
Benzoic acid and 2-phenylacetic acid, were found to posses weak free radical-scavenging activity.