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Chemical investigation of the culture of Fusarium semitectum isolated from a dead cicada skin collected in Indonesia has
yielded three new tetrapeptides, namely apicidins E - G (1 – 3) together with the new polyketide 4 and six known compounds.
The structures of the new metabolites were deduced by NMR and mass spectrometry, while the structure of polyketide 4,
possessing an unusual eight-membered ring, was further confirmed by methylation to the methoxy derivative 5. Based on the
result of this study together with earlier reports from the literature, we can suggest that tetrapeptide apicidin and its congeners
are possibly chemotaxonomic markers of this fungal species.