Aims and Scope

The Open Neurology Journal is an Open Access journal, which publishes high quality research articles, reviews/mini-reviews, letters and guest edited single topic issues in all important areas of neurology and neurological disorders. The scope of the journal includes:

  • Neurological progress
  • Neurological and psychiatric therapies
  • Stem cell applications
  • Biomathematical models
  • Neuroradiology
  • Molecular neuroscience
  • Neuropharmacology
  • Neurochemistry
The Open Neurology Journal, a peer-reviewed journal, is an important and reliable source of current information on important developments in the field. Emphasis is placed on publishing quality papers, making them freely available to researchers worldwide.


Recent Articles

Editor's Choice

Association Between a Functional Polymorphism in the Monoamine Oxidase A (MAOA) Gene and Both Emotional Coping Style and Neuroticism

Diego A. Forero, Ana Adan, Sandra Lopez-Leon

Background:

Identification of novel genetic factors for Depressive Disorders (DD) represents a major challenge around the world. Molecular studies of endophenotypes associated with DD, such as personality traits and coping, are powerful strategies for finding genetic markers.

Objective:

The main objective of this work was to confirm the potential relationship between a functional polymorphism in the monoamine oxidase A (MAOA) gene and scores in coping and neuroticism in young adults.

Methods:

A Colombian sample of two hundred fifty-one young participants was evaluated with the short forms of the Coping Inventory for Stressful Situations (CISS-SF) and the Big Five Inventory (BFI-S). Genotypes for MAOA-VNTR polymorphism were obtained by PCR.

Results:

A significant relationship between the functional MAOA-VNTR polymorphism and scores in both emotion-oriented coping and neuroticism was found. Individuals carrying the 4 allele (3/4 or 4/4 genotypes) had higher scores for both emotion-oriented coping and neuroticism than individuals with a 3/3 genotype.

Conclusion:

Our current findings are novel in terms of being the first report of a relationship between a functional polymorphism in the MAOA gene and coping and add evidence to the association of this gene with neuroticism. Our results expand the associations between MAOA gene and multiple dimensions of human emotion and personality.


June 16, 2020
READ MORE

Quick Links

Indexing Agencies

READ MORE

Archived In