The Open Nutrition Journal


ISSN: 1874-2882 ― Volume 11, 2017
RESEARCH ARTICLE

The Efficacy of Curcumin on Cognition, Depression, and Agitation in Older Adults with Alzheimer’s Disease



Jyotsna Sharman1, *, Roofia Galeshi2, Lisa Onega3, Susanne Ashby4, Kavya Sharman5
1 Department of Health and Human Performance, Radford University, Radford, VA, USA
2 School of Teacher Education and Leadership, Radford University, Radford, VA, USA
3 School of Nursing, Radford University, Radford, VA, USA
4 Independent Education Researcher & Program Evaluator, San Diego, CA, USA
5 Vanderbilt University Medical Center, Nashville, TN, USA

Abstract

The purpose of this systematic review was to ascertain the current state of science regarding the use of turmeric and its pigment curcumin in individuals with Alzheimer’s Disease (AD). A summary of qualitative and quantitative evidence specific to the effect of curcumin on AD is presented in this article. The purpose of the review was to evaluate and summarize findings related to this body of research. Findings indicated a positive correlation between administration of turmeric and improvement AD symptoms; however, long-term benefits need to be researched. Also, experimental research with older adults with mild, moderate, and severe AD should be conducted to determine whether or not turmeric and curcumin improve cognition, depression, and agitation. Specific methodological issues that need to be considered are the dosage and purity of turmeric and curcumin, administration frequency, determination of a suitable placebo, and duration of testing.

Keywords: Curcumin, Cognition, Depression, Older Adults, Alzheimer’s Disease, Dementia.


Article Information


Identifiers and Pagination:

Year: 2017
Volume: 11
First Page: 11
Last Page: 16
Publisher Id: TONUTRJ-11-11
DOI: 10.2174/1874288201711010011

Article History:

Received Date: 30/10/2016
Revision Received Date: 23/12/2016
Acceptance Date: 25/12/2016
Electronic publication date: 31/01/2017
Collection year: 2017

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© Sharman et al.; Licensee Bentham Open

open-access license: This is an open access article licensed under the terms of the Creative Commons Attribution-Non-Commercial 4.0 International Public License (CC BY-NC 4.0) (https://creativecommons.org/licenses/by-nc/4.0/legalcode), which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.


* Address correspondence to this author at the Department of Health and Human Performance, Radford University, Radford, VA, USA; Tel: Home: (870) 210-2522; Fax: (540) 831-6650; E-mail: jsharman2@radford.edu


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